During clinical trials to approve a drug, the ideal dosage is defined based on the average response of patients in the study population.
In general terms:
- During development, the drug is tested on several people
- If the drug works for a reasonable number of individuals, it tends to be accepted and sold to the public
- The dosage that worked best during the tests is reported on the package leaflet and suggested as the standard dose. However, a significant proportion do not respond adequately.
- Test cases with adverse reactions and other observed occurrences are included in the package leaflet, which is why many side effects and contraindications are often listed
The same drugs and doses are prescribed for everyone, even though each of us processes them differently
- Medicines that are good for some can be toxic for others
- In addition, some people metabolize the drug more quickly and others more slowly
- Consequently, the dose, frequency and medication should ideally be prescribed with this in mind
- Doctors basically rely on the patient’s experience and history to prescribe a drug
- Doctors will probably only know that there is a problem with the drug after testing it. They have little information to make an individualized prior adjustment
Pharmacogenetics (or pharmacogenomics) is the study of how DNA influences the response to each drug
- The main factors that influence the response to a drug are: genetics, age, diseases, immunological factors and drug interactions
- Your genes tell you, for example, whether you produce more or less of an enzyme needed to process a drug
- Or if you have a mutation that makes the drug totally or partially ineffective.
Conheça algumas vantagens dos exames Farmacogenéticos da ConectGene:
O remédio certo desde de o começo
Os médicos contam basicamente com a experiência e o histórico do paciente para prescrever o medicamento. Evite a tentativa e erro e dê a ele mais uma ferramenta para decidir o que funciona para você.
Evite medicamentos tóxicos
Variações genéticas podem indicar se um medicamento é tóxico ou se apresenta chances de lhe causar efeitos colaterais.
Ajuste a dose para o seu organismo
Descubra se seu corpo metaboliza o medicamento rápido ou devagar e permita que seu médico ajuste a dosagem para o seu caso específico.
Um exame para a vida inteira
Nossos testes avaliam diversos medicamentos. Reapresente seu exame sempre que for a um novo médico ou que realizar um novo tratamento.
